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Functionalised nano-diamond solutions

Discover the EVADIA-NDF solution
and choose the functionalisation of your nano-diamonds!

WAINVAM-E develops the EVADIA-NDF solution, a range of functionalised nanodiamonds with NV centres. Functionalisation of nanodiamonds means modifying their surface to allow binding with chemicals or biomolecules to improve their properties and to bind them precisely to targeted locations.

We offer nanodiamonds in solution, functionalised with polyethylene glycol (PEG) molecules, and are working on other functionalisations for the detection of various pathogens (dengue fever, bacteria responsible of the Lyme disease), of various biomarkers (such as biomarkers of lung cancer) and of various chemicals (antibiotics for example).

PEGs are a class of biocompatible carbon chains frequently used in chemistry and biology.

The length of the carbon chain and the terminal chemical group can be adapted to the needs. With this PEG function, it will be possible to link your molecule of choice onto the nanodiamonds to form a fluorescent and photo-stable conjugate.

Applications

EVADIA-PEG fluorescent nano-diamonds can be used in physiological environments

  • As markers: The conjugate formed by your molecule fixed on the nano diamonds can be used as fluorescent marker to detect or track other target molecules
  • As sensors: The molecule to be fixed on the nano diamond can be chosen so that the nano diamonds are directed to a specific area. There, the properties of the NV center nanodiamonds can be used to measure the variation of physical parameters such magnetic field.
  • As carriers: The nanodiamond can be used as a carrier of your active molecule (for e.g., a drug) fixed on it via the PEG linker.

Technical specifications

Sizes: 70, 100 or 140 nm
Available PEG amine chain lengths: ~5, 10, 23, 44
Volumes: 5 or 10mL (suspension in deionized water)
Concentration: 1 mg/mL
Guaranteed stability: 5 months
Storage conditions: 4° C
Shipping conditions: 4°C, box with ice pad

On demand, we can customize your PEG (e.g. PEG acid, PEG azide with different chain lengths)

Fields

Biomedical Cosmetics Agri-food Pharmaceutical

Associated equipment

WAINVIEW Relaxometer WAINVIEW Microscope Fluorescence or confocal microscope Pharmaceutical

Safety Datasheet

Download the datasheet

Discover
the EVADIA-NDF solution

In the EVADIA-NDF solution, the fluorescent nano-diamonds are functionalised with streptavidin molecules.
Streptavidin is a protein that has a high affinity for biotin. Biotin is a coenzyme present in all living species that can bind to different molecules of interest. Therefore, EVADIA-NDF functionalised nano-diamonds allow the binding to biotin molecules, to serve as markers and transporters in physiological environments.

Applications

EVADIA-NDF fluorescent nano-diamonds can be used in physiological environments

  • As markers to label and detect your molecule of interest.
  • As transporters, to deliver a molecule of interest to a specific site.

Technical characteristics

Size: 100nm
Volume: 10mL
Concentration: 1 mg/mL

Fields

Biomedical Cosmetics Agri-food

Associated equipment

WAINVIEW Microscope Flow cytometer Fluorescence or confocal microscope

Quantum physics practical work with WAINTEACH

1. Spin resonance and Zeeman effect The NV centre of a diamond has an electron spin S=1. Therefore, three fine levels can be distinguished, corresponding to the projection of the spin on the axis of the NV centre, |𝑚_𝑠=0, ±1⟩. When illuminated with a green

Quantum sensors

A quantum sensor is a measuring instrument that exploits the laws of quantum mechanics and provides the measurement of physical quantities directly from values of fundamental constants of quantum physics. Such a sensor is therefore inherently accurate and stable, both being essential properties for many

Oxidative stress

Oxidative stress is involved in many phenomena ranging from a simple burn to serious diseases such as cancer, infectious diseases or neurodegenerative diseases. It is promoted by internal mechanisms such as infections or deficiencies, as well as by external factors such as smoking, sun exposure

The operation of a NV magnetometer

Magnetometry refers to the general principle of measuring the magnetic field of a system in order to study or characterise certain properties. The sensor with which magnetometry measurements are made is called a magnetometer. At WAINVAM-E we develop magnetometers using the optical and quantum properties

Do not hesitate to contact us if you need any further information

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Quantum physics practical work with WAINTEACH

1. Spin resonance and Zeeman effect The NV centre of a diamond has an electron spin S=1. Therefore, three fine levels can be distinguished, corresponding to the projection of the spin on the axis of the NV centre, |𝑚_𝑠=0, ±1⟩. When illuminated with a green

Quantum sensors

A quantum sensor is a measuring instrument that exploits the laws of quantum mechanics and provides the measurement of physical quantities directly from values of fundamental constants of quantum physics. Such a sensor is therefore inherently accurate and stable, both being essential properties for many

Oxidative stress

Oxidative stress is involved in many phenomena ranging from a simple burn to serious diseases such as cancer, infectious diseases or neurodegenerative diseases. It is promoted by internal mechanisms such as infections or deficiencies, as well as by external factors such as smoking, sun exposure

The operation of a NV magnetometer

Magnetometry refers to the general principle of measuring the magnetic field of a system in order to study or characterise certain properties. The sensor with which magnetometry measurements are made is called a magnetometer. At WAINVAM-E we develop magnetometers using the optical and quantum properties
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